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Induction of apoptosis coupled to endoplasmic reticulum stress in human prostate cancer cells by n-butylidenephthalide.

Chiu, Sheng-Chun

Induction of apoptosis coupled to endoplasmic reticulum stress in human prostate cancer cells by n-butylidenephthalide. [electronic resource] - PloS one 2012 - e33742 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

ISSN: 1932-6203

Standard No.: 10.1371/journal.pone.0033742 doi

Subjects--Topical Terms:
Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cell Line, Tumor
Cyclin-Dependent Kinase Inhibitor p16--metabolism
Cyclin-Dependent Kinase Inhibitor p21--metabolism
Cyclin-Dependent Kinase Inhibitor p27--metabolism
Endoplasmic Reticulum Chaperone BiP
Endoplasmic Reticulum Stress--drug effects
Endoribonucleases--antagonists & inhibitors
G1 Phase Cell Cycle Checkpoints
Humans
Male
Mice
Mice, Inbred NOD
Mitogen-Activated Protein Kinase 8--antagonists & inhibitors
Mitogen-Activated Protein Kinase 9--antagonists & inhibitors
Phthalic Anhydrides--pharmacology
Prostatic Neoplasms
Protein Serine-Threonine Kinases--antagonists & inhibitors
RNA Interference
RNA, Small Interfering--metabolism
Signal Transduction
Transcription Factor CHOP--antagonists & inhibitors
Transplantation, Heterologous