Anti-tumoural effects of PlgK1-5 are directly linked to reduced ICAM expression, resulting in hepatoma cell apoptosis.

Schmitz, Volker

Anti-tumoural effects of PlgK1-5 are directly linked to reduced ICAM expression, resulting in hepatoma cell apoptosis. [electronic resource] - International journal of colorectal disease Aug 2012 - 1029-38 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1432-1262

10.1007/s00384-012-1418-6 doi


Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Carcinoma, Hepatocellular--drug therapy
Caspase 8--metabolism
Cell Adhesion Molecules--metabolism
Cell Line, Tumor
Cell Movement--drug effects
Cell Proliferation--drug effects
Clone Cells
Gene Expression Regulation, Neoplastic--drug effects
Humans
Immunohistochemistry
Intercellular Adhesion Molecule-1--genetics
Intracellular Space--drug effects
Liver Neoplasms--drug therapy
Mice
Phosphorylation--drug effects
Plasminogen--pharmacology
Proto-Oncogene Proteins c-akt--metabolism
Signal Transduction--drug effects
Subcutaneous Tissue--drug effects
p38 Mitogen-Activated Protein Kinases--metabolism