Design and synthesis of thiourea derivatives containing a benzo[5,6]cyclohepta[1,2-b]pyridine moiety as potential antitumor and anti-inflammatory agents.

Liu, Wukun

Design and synthesis of thiourea derivatives containing a benzo[5,6]cyclohepta[1,2-b]pyridine moiety as potential antitumor and anti-inflammatory agents. [electronic resource] - Bioorganic & medicinal chemistry letters Apr 2012 - 2701-4 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1464-3405

10.1016/j.bmcl.2012.03.002 doi


Animals
Anti-Inflammatory Agents--chemical synthesis
Antineoplastic Agents--chemical synthesis
Biological Assay
Breast Neoplasms--drug therapy
Cell Line, Tumor
Cell Proliferation--drug effects
Colonic Neoplasms--drug therapy
Cyclization
Disease Models, Animal
Drug Design
Female
Humans
Inhibitory Concentration 50
Mice
Pyrimidines--chemical synthesis
Thiourea--chemical synthesis