Translocation of a Bak C-terminus mutant from cytosol to mitochondria to mediate cytochrome C release: implications for Bak and Bax apoptotic function.

Ferrer, Pedro Eitz

Translocation of a Bak C-terminus mutant from cytosol to mitochondria to mediate cytochrome C release: implications for Bak and Bax apoptotic function. [electronic resource] - PloS one 2012 - e31510 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0031510 doi


Animals
Apoptosis--physiology
Cell Line, Transformed
Cytochromes c--genetics
Cytosol--metabolism
Mice
Mice, Knockout
Mitochondria--genetics
Mutation
Myeloid Cell Leukemia Sequence 1 Protein
Protein Transport--physiology
Proto-Oncogene Proteins c-bcl-2--genetics
bcl-2 Homologous Antagonist-Killer Protein--genetics
bcl-2-Associated X Protein--genetics