Endothelial HIF-2α regulates murine pathological angiogenesis and revascularization processes.

Skuli, Nicolas

Endothelial HIF-2α regulates murine pathological angiogenesis and revascularization processes. [electronic resource] - The Journal of clinical investigation Apr 2012 - 1427-43 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1558-8238

10.1172/JCI57322 doi


Adaptor Proteins, Signal Transducing
Angiopoietin-2--genetics
Animals
Basic Helix-Loop-Helix Transcription Factors--deficiency
Calcium-Binding Proteins
Cell Hypoxia
Cell Movement
Cells, Cultured--cytology
Collateral Circulation--physiology
Endothelial Cells--metabolism
Hindlimb--blood supply
Hypoxia-Inducible Factor 1, alpha Subunit--deficiency
Intracellular Signaling Peptides and Proteins--genetics
Ischemia--physiopathology
Membrane Proteins--genetics
Mice
Mice, Inbred C57BL
Mice, Knockout
Mice, Transgenic
Neovascularization, Pathologic--physiopathology
Neovascularization, Physiologic--physiology
Receptors, Notch--physiology
Recombinant Fusion Proteins--physiology
Recovery of Function
Skin Neoplasms--blood supply
Wound Healing--physiology