Malignant germ cell-like tumors, expressing Ki-1 antigen (CD30), are revealed during in vivo differentiation of partially reprogrammed human-induced pluripotent stem cells.

Griscelli, Frank

Malignant germ cell-like tumors, expressing Ki-1 antigen (CD30), are revealed during in vivo differentiation of partially reprogrammed human-induced pluripotent stem cells. [electronic resource] - The American journal of pathology May 2012 - 2084-96 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1525-2191

10.1016/j.ajpath.2012.01.011 doi


Animals
Cell Differentiation--physiology
Cell Proliferation
Cell Transformation, Neoplastic--genetics
Cellular Reprogramming--physiology
Embryonic Stem Cells--cytology
Gene Expression Regulation, Neoplastic
Gene Silencing
Humans
Induced Pluripotent Stem Cells--metabolism
Karyotype
Ki-1 Antigen--metabolism
Kruppel-Like Factor 4
Mice
Mice, Inbred NOD
Mice, SCID
Neoplasms, Germ Cell and Embryonal--genetics
Teratoma--metabolism
Transgenes--genetics