Narciclasine as well as other Amaryllidaceae isocarbostyrils are promising GTP-ase targeting agents against brain cancers.

Van Goietsenoven, Gwendoline

Narciclasine as well as other Amaryllidaceae isocarbostyrils are promising GTP-ase targeting agents against brain cancers. [electronic resource] - Medicinal research reviews Mar 2013 - 439-55 p. digital

Publication Type: Journal Article; Review

1098-1128

10.1002/med.21253 doi


Amaryllidaceae Alkaloids--adverse effects
Animals
Apoptosis--drug effects
Brain Neoplasms--drug therapy
Cohort Studies
Cytotoxins--pharmacology
Disease Models, Animal
Dose-Response Relationship, Drug
GTP Phosphohydrolases--drug effects
Glioblastoma--drug therapy
Humans
In Vitro Techniques
Melanoma--drug therapy
Mice
Molecular Targeted Therapy
Neoplasms--drug therapy
Phenanthridines--adverse effects
Structure-Activity Relationship
Transplantation, Heterologous
Treatment Outcome