The 5-hydroxytryptamine4 receptor agonists prucalopride and PRX-03140 increase acetylcholine and histamine levels in the rat prefrontal cortex and the power of stimulated hippocampal θ oscillations.

Johnson, David E

The 5-hydroxytryptamine4 receptor agonists prucalopride and PRX-03140 increase acetylcholine and histamine levels in the rat prefrontal cortex and the power of stimulated hippocampal θ oscillations. [electronic resource] - The Journal of pharmacology and experimental therapeutics Jun 2012 - 681-91 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1521-0103

10.1124/jpet.112.192351 doi


Acetylcholine--metabolism
Animals
Area Under Curve
Benzofurans--pharmacology
Chromatography, High Pressure Liquid
Electroencephalography
Hippocampus--drug effects
Histamine--metabolism
Humans
Male
Microdialysis
Prefrontal Cortex--drug effects
Pyridones--pharmacology
Rats
Rats, Sprague-Dawley
Receptors, Serotonin, 5-HT4--metabolism
Serotonin--chemistry
Serotonin 5-HT4 Receptor Agonists--pharmacology
Tandem Mass Spectrometry
Thiophenes--pharmacology