Thrombin receptor antagonists. Structure-activity relationships for the platelet thrombin receptor and effects on prostacyclin synthesis by human umbilical vein endothelial cells.

Ruda, E M

Thrombin receptor antagonists. Structure-activity relationships for the platelet thrombin receptor and effects on prostacyclin synthesis by human umbilical vein endothelial cells. [electronic resource] - Biochemical pharmacology Jan 1990 - 373-81 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-2952

10.1016/0006-2952(90)90037-l doi


Antithrombins--chemical synthesis
Blood Platelets--drug effects
Cells, Cultured
Chemical Phenomena
Chemistry
Chymotrypsin--pharmacology
Dose-Response Relationship, Drug
Endothelium, Vascular--drug effects
Epoprostenol--biosynthesis
Humans
Peptides--chemical synthesis
Platelet Aggregation--drug effects
Receptors, Cell Surface--drug effects
Receptors, Thrombin
Structure-Activity Relationship
Thrombin--pharmacology