Increased secretion of tissue inhibitors of metalloproteinases 1 and 2 (TIMPs -1 and -2) in fibroblasts are early indicators of oral sub-mucous fibrosis and ageing.

Pitiyage, Gayani N

Increased secretion of tissue inhibitors of metalloproteinases 1 and 2 (TIMPs -1 and -2) in fibroblasts are early indicators of oral sub-mucous fibrosis and ageing. [electronic resource] - Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology Jul 2012 - 454-62 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

1600-0714

10.1111/j.1600-0714.2012.01129.x doi


Adolescent
Adult
Aged
Biomarkers--analysis
Case-Control Studies
Cell Culture Techniques
Cellular Senescence
Collagen Type I--analysis
Culture Media, Conditioned
DNA Damage
Epithelium--pathology
Fibroblasts--enzymology
Humans
Matrix Metalloproteinase 1--analysis
Matrix Metalloproteinase 2--analysis
Matrix Metalloproteinase 3--analysis
Matrix Metalloproteinase 9--analysis
Mesoderm--pathology
Middle Aged
Oral Submucous Fibrosis--enzymology
Protease Inhibitors--analysis
Tissue Inhibitor of Metalloproteinase-1--analysis
Tissue Inhibitor of Metalloproteinase-2--analysis
Transforming Growth Factor beta1--analysis
Young Adult