2-Morpholinoisoflav-3-enes as flexible intermediates in the synthesis of phenoxodiol, isophenoxodiol, equol and analogues: vasorelaxant properties, estrogen receptor binding and Rho/RhoA kinase pathway inhibition.
Tilley, Andrew J
2-Morpholinoisoflav-3-enes as flexible intermediates in the synthesis of phenoxodiol, isophenoxodiol, equol and analogues: vasorelaxant properties, estrogen receptor binding and Rho/RhoA kinase pathway inhibition. [electronic resource] - Bioorganic & medicinal chemistry Apr 2012 - 2353-61 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1464-3391
10.1016/j.bmc.2012.02.008 doi
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid--toxicity
Animals
Equol--analogs & derivatives
Isoflavones--chemical synthesis
Male
Morpholines--chemistry
Protein Binding
Protein Kinase Inhibitors--chemical synthesis
Rats
Rats, Sprague-Dawley
Receptors, Estrogen--chemistry
Vasoconstriction--drug effects
Vasodilator Agents--chemical synthesis
rho-Associated Kinases--antagonists & inhibitors
2-Morpholinoisoflav-3-enes as flexible intermediates in the synthesis of phenoxodiol, isophenoxodiol, equol and analogues: vasorelaxant properties, estrogen receptor binding and Rho/RhoA kinase pathway inhibition. [electronic resource] - Bioorganic & medicinal chemistry Apr 2012 - 2353-61 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1464-3391
10.1016/j.bmc.2012.02.008 doi
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid--toxicity
Animals
Equol--analogs & derivatives
Isoflavones--chemical synthesis
Male
Morpholines--chemistry
Protein Binding
Protein Kinase Inhibitors--chemical synthesis
Rats
Rats, Sprague-Dawley
Receptors, Estrogen--chemistry
Vasoconstriction--drug effects
Vasodilator Agents--chemical synthesis
rho-Associated Kinases--antagonists & inhibitors