Synergistic effects of central nervous system-directed gene therapy and bone marrow transplantation in the murine model of infantile neuronal ceroid lipofuscinosis.

Macauley, Shannon L

Synergistic effects of central nervous system-directed gene therapy and bone marrow transplantation in the murine model of infantile neuronal ceroid lipofuscinosis. [electronic resource] - Annals of neurology Jun 2012 - 797-804 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1531-8249

10.1002/ana.23545 doi


Age Factors
Animals
Animals, Newborn
Bone Marrow Transplantation--methods
Brain--metabolism
Dependovirus--genetics
Disease Models, Animal
Female
Genetic Therapy--methods
Genetic Vectors--administration & dosage
Male
Mice
Mice, Knockout
Motor Activity
Neuronal Ceroid-Lipofuscinoses--pathology
Rotarod Performance Test
Thiolester Hydrolases--biosynthesis