Improvement of replication fidelity by certain mesalazine derivatives.

Honeder, Clemens

Improvement of replication fidelity by certain mesalazine derivatives. [electronic resource] - International journal of oncology May 2012 - 1331-8 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

1791-2423

10.3892/ijo.2012.1381 doi


Adaptor Proteins, Signal Transducing--genetics
Anticarcinogenic Agents--pharmacology
Ataxia Telangiectasia Mutated Proteins
Cell Cycle Checkpoints--drug effects
Cell Cycle Proteins--metabolism
Cell Proliferation--drug effects
Checkpoint Kinase 1
Colorectal Neoplasms--genetics
DNA Replication--drug effects
Dose-Response Relationship, Drug
Free Radical Scavengers--pharmacology
HCT116 Cells
HT29 Cells
Humans
Mesalamine--pharmacology
MutL Protein Homolog 1
Mutation
Nuclear Proteins--genetics
Oxidative Stress--drug effects
Protein Kinases--metabolism
Protein Serine-Threonine Kinases--metabolism
Signal Transduction--drug effects
Superoxides--metabolism
Transfection
Tumor Suppressor Protein p53--genetics