Liver-specific expression of transcriptionally active SREBP-1c is associated with fatty liver and increased visceral fat mass.

Knebel, Birgit

Liver-specific expression of transcriptionally active SREBP-1c is associated with fatty liver and increased visceral fat mass. [electronic resource] - PloS one 2012 - e31812 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0031812 doi


Acetyltransferases--metabolism
Adipocytes--drug effects
Adiposity--drug effects
Animals
Body Composition--drug effects
Cytokines--blood
Fatty Acid Elongases
Fatty Acids--metabolism
Fatty Liver--blood
Gene Expression Regulation--drug effects
Humans
Insulin--pharmacology
Insulin Resistance
Intra-Abdominal Fat--drug effects
Lipogenesis--drug effects
Liver--drug effects
Male
Mice
Mice, Transgenic
Organ Size--drug effects
Organ Specificity--drug effects
Phenotype
Protein Structure, Tertiary
Stearoyl-CoA Desaturase--metabolism
Sterol Regulatory Element Binding Protein 1--chemistry
Transcription, Genetic--drug effects