Phase Ia clinical evaluation of the safety and immunogenicity of the Plasmodium falciparum blood-stage antigen AMA1 in ChAd63 and MVA vaccine vectors.

Sheehy, Susanne H

Phase Ia clinical evaluation of the safety and immunogenicity of the Plasmodium falciparum blood-stage antigen AMA1 in ChAd63 and MVA vaccine vectors. [electronic resource] - PloS one 2012 - e31208 p. digital

Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0031208 doi


Adenoviruses, Simian--genetics
Adolescent
Adult
Animals
Antibodies, Neutralizing--immunology
Antibodies, Protozoan--immunology
Antigens, Protozoan--immunology
Enzyme-Linked Immunospot Assay
Female
Genetic Vectors--genetics
Humans
Immunization
Interferon-gamma--immunology
Life Cycle Stages
Malaria Vaccines--adverse effects
Malaria, Falciparum--immunology
Male
Middle Aged
Plasmodium falciparum--growth & development
T-Lymphocytes--immunology
Vaccinia virus--genetics
Young Adult