IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype.

Turcan, Sevin

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. [electronic resource] - Nature Feb 2012 - 479-83 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1476-4687

10.1038/nature10866 doi


Astrocytes--cytology
Cell Survival--genetics
Cells, Cultured
CpG Islands--genetics
DNA Methylation--genetics
Epigenesis, Genetic
Epigenomics
Gene Expression Regulation
Glioblastoma--genetics
Glioma--genetics
HEK293 Cells
Histones--metabolism
Humans
Isocitrate Dehydrogenase--genetics
Metabolome--genetics
Mutation--genetics
Phenotype
Tumor Cells, Cultured