Tuning and predicting biological affinity: aryl nitriles as cysteine protease inhibitors.

Ehmke, Veronika

Tuning and predicting biological affinity: aryl nitriles as cysteine protease inhibitors. [electronic resource] - Organic & biomolecular chemistry Aug 2012 - 5764-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1477-0539

10.1039/c2ob00034b doi


Catalytic Domain
Cathepsin L--antagonists & inhibitors
Cysteine Endopeptidases--chemistry
Cysteine Proteinase Inhibitors--chemical synthesis
Drug Design
Humans
Models, Molecular
Nitriles--chemical synthesis
Trypanosoma brucei brucei--enzymology