An isoniazid analogue promotes Mycobacterium tuberculosis-nanoparticle interactions and enhances bacterial killing by macrophages.

de Faria, Tatiany J

An isoniazid analogue promotes Mycobacterium tuberculosis-nanoparticle interactions and enhances bacterial killing by macrophages. [electronic resource] - Antimicrobial agents and chemotherapy May 2012 - 2259-67 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1098-6596

10.1128/AAC.05993-11 doi


Animals
Antitubercular Agents--pharmacology
Biological Availability
Cells, Cultured
Drug Compounding
Drug Delivery Systems--methods
Hydrogen-Ion Concentration
Hydrophobic and Hydrophilic Interactions
Isoniazid--analogs & derivatives
Lactic Acid--chemistry
Macrophages--drug effects
Mice
Microscopy, Atomic Force
Microscopy, Confocal
Mycobacterium tuberculosis--drug effects
Nanoparticles
Particle Size
Phagocytosis
Polyglycolic Acid--chemistry
Polylactic Acid-Polyglycolic Acid Copolymer
Tuberculosis, Pulmonary--drug therapy