The phosphodiesterases type 5 inhibitor tadalafil reduces the activation of the hypothalamus-pituitary-adrenal axis in men during cycle ergometric exercise.

Di Luigi, Luigi

The phosphodiesterases type 5 inhibitor tadalafil reduces the activation of the hypothalamus-pituitary-adrenal axis in men during cycle ergometric exercise. [electronic resource] - American journal of physiology. Endocrinology and metabolism Apr 2012 - E972-8 p. digital

Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial

1522-1555

10.1152/ajpendo.00573.2011 doi


Adrenal Cortex Hormones--blood
Adult
Athletic Performance
Bicycling
Carbolines--pharmacology
Carrier Proteins--blood
Cross-Over Studies
Double-Blind Method
Humans
Hypothalamic Hormones--blood
Hypothalamo-Hypophyseal System--drug effects
Lactic Acid--blood
Male
Oxygen Consumption--drug effects
Phosphodiesterase 5 Inhibitors--pharmacology
Physical Exertion
Pituitary Hormones--blood
Pituitary-Adrenal System--drug effects
Stress, Physiological--drug effects
Tadalafil
Young Adult