Mutated major histocompatibility complex class II transactivator up-regulates interleukin-33-dependent differentiation of Th2 subset through Nod2 binding for NLR (NOD-like receptor) signaling initiation.

Yang, Zhiqiang

Mutated major histocompatibility complex class II transactivator up-regulates interleukin-33-dependent differentiation of Th2 subset through Nod2 binding for NLR (NOD-like receptor) signaling initiation. [electronic resource] - The Journal of biological chemistry Mar 2012 - 9972-9981 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.M111.288498 doi


Adaptor Proteins, Signal Transducing--genetics
Animals
Caspase 1--genetics
Cell Line
Cytokines--genetics
Histocompatibility Antigens Class II--biosynthesis
Interleukin-33
Interleukins--genetics
Mice
Mice, Inbred BALB C
Mice, Transgenic
Mutation
Nod2 Signaling Adaptor Protein--genetics
Nuclear Proteins--genetics
Receptor-Interacting Protein Serine-Threonine Kinase 2
Receptor-Interacting Protein Serine-Threonine Kinases--genetics
Signal Transduction--physiology
Th1 Cells--immunology
Th2 Cells--immunology
Trans-Activators--genetics
Transplantation Tolerance--physiology
Up-Regulation--physiology