A synthetic heparan sulfate-mimetic peptide conjugated to a mini CD4 displays very high anti- HIV-1 activity independently of coreceptor usage.

Connell, Bridgette Janine

A synthetic heparan sulfate-mimetic peptide conjugated to a mini CD4 displays very high anti- HIV-1 activity independently of coreceptor usage. [electronic resource] - Chemistry & biology Jan 2012 - 131-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1879-1301

10.1016/j.chembiol.2011.12.009 doi


Amino Acid Sequence
Anti-HIV Agents--chemical synthesis
Binding Sites
CD4 Antigens--chemistry
Cell Membrane--metabolism
HIV Envelope Protein gp120--chemistry
HIV-1--drug effects
Heparitin Sulfate--chemistry
Humans
Peptides--chemical synthesis
Protein Binding
Receptors, CCR5--chemistry
Receptors, CXCR4--chemistry
Virus Replication--drug effects