A new strategy for the development of highly potent and selective plasmin inhibitors.

Saupe, Sebastian M

A new strategy for the development of highly potent and selective plasmin inhibitors. [electronic resource] - Journal of medicinal chemistry Feb 2012 - 1171-80 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1520-4804

10.1021/jm2011996 doi


Amino Acid Sequence
Antifibrinolytic Agents--chemical synthesis
Cyclization
Dipeptides--chemical synthesis
Enzyme Assays
Fibrinolysin--metabolism
Kinetics
Models, Molecular
Molecular Sequence Data
Peptides, Cyclic--chemical synthesis
Peptidomimetics--chemical synthesis
Protein Conformation
Stereoisomerism
Structure-Activity Relationship
Triazoles--chemical synthesis