Autocrine prostaglandin E2 signaling promotes tumor cell survival and proliferation in childhood neuroblastoma.

Rasmuson, Agnes

Autocrine prostaglandin E2 signaling promotes tumor cell survival and proliferation in childhood neuroblastoma. [electronic resource] - PloS one 2012 - e29331 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0029331 doi


16,16-Dimethylprostaglandin E2--pharmacology
Autocrine Communication--drug effects
Biphenyl Compounds--pharmacology
Blotting, Western
Calcium--metabolism
Cell Line, Tumor
Cell Proliferation--drug effects
Cell Survival--drug effects
Cyclic AMP--metabolism
Cyclooxygenase 2 Inhibitors--pharmacology
Dinoprostone--metabolism
Humans
Immunohistochemistry
In Vitro Techniques
Neuroblastoma--metabolism
Phosphorylation--drug effects
Receptors, Prostaglandin E, EP1 Subtype--antagonists & inhibitors
Receptors, Prostaglandin E, EP2 Subtype--antagonists & inhibitors
Receptors, Prostaglandin E, EP3 Subtype--antagonists & inhibitors
Receptors, Prostaglandin E, EP4 Subtype--antagonists & inhibitors
Reverse Transcriptase Polymerase Chain Reaction
Tandem Mass Spectrometry
Thiophenes--pharmacology
Triazoles--pharmacology