The scaffolding protein Dlg1 is a negative regulator of cell-free virus infectivity but not of cell-to-cell HIV-1 transmission in T cells.

Nzounza, Patrycja

The scaffolding protein Dlg1 is a negative regulator of cell-free virus infectivity but not of cell-to-cell HIV-1 transmission in T cells. [electronic resource] - PloS one 2012 - e30130 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0030130 doi


Adaptor Proteins, Signal Transducing--genetics
Cell Communication
Cell Line, Tumor
Cells, Cultured
Cholesterol--metabolism
Coculture Techniques
DNA, Viral--genetics
Discs Large Homolog 1 Protein
Green Fluorescent Proteins--genetics
HEK293 Cells
HIV-1--genetics
HeLa Cells
Host-Pathogen Interactions
Humans
Immunological Synapses--metabolism
Jurkat Cells
Kinetics
Membrane Proteins--genetics
Microscopy, Confocal
Microscopy, Electron
RNA Interference
T-Lymphocytes--metabolism
Virus Replication--genetics