Elevation in body temperature to fever range enhances and prolongs subsequent responsiveness of macrophages to endotoxin challenge.

Lee, Chen-Ting

Elevation in body temperature to fever range enhances and prolongs subsequent responsiveness of macrophages to endotoxin challenge. [electronic resource] - PloS one 2012 - e30077 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1932-6203

10.1371/journal.pone.0030077 doi


Animals
Body Temperature--drug effects
Female
Fever--complications
Gene Expression Regulation--drug effects
HSP70 Heat-Shock Proteins--metabolism
Hot Temperature
Inflammation--complications
Inflammation Mediators--metabolism
Interferon-gamma--pharmacology
Lipopolysaccharides--pharmacology
Macrophage Activation--drug effects
Macrophages, Peritoneal--drug effects
Mice
Mice, Inbred BALB C
NF-kappa B--metabolism
Tumor Necrosis Factor-alpha--biosynthesis