Binding evaluation of fragment-based scaffolds for probing allosteric enzymes.
Krimm, Isabelle
Binding evaluation of fragment-based scaffolds for probing allosteric enzymes. [electronic resource] - Journal of medicinal chemistry Feb 2012 - 1287-95 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-4804
10.1021/jm201439b doi
Allosteric Regulation
Binding Sites
Enzyme Inhibitors--chemistry
Glycogen Phosphorylase--antagonists & inhibitors
Ligands
Magnetic Resonance Spectroscopy
Models, Molecular
Protein Binding
Structure-Activity Relationship
Binding evaluation of fragment-based scaffolds for probing allosteric enzymes. [electronic resource] - Journal of medicinal chemistry Feb 2012 - 1287-95 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-4804
10.1021/jm201439b doi
Allosteric Regulation
Binding Sites
Enzyme Inhibitors--chemistry
Glycogen Phosphorylase--antagonists & inhibitors
Ligands
Magnetic Resonance Spectroscopy
Models, Molecular
Protein Binding
Structure-Activity Relationship