Synthesis of 3-phenylsulfonylmethyl cyclohexylaminobenzamide-derived antagonists of CC chemokine receptor 2 (CCR2).
Yang, Michael G
Synthesis of 3-phenylsulfonylmethyl cyclohexylaminobenzamide-derived antagonists of CC chemokine receptor 2 (CCR2). [electronic resource] - Bioorganic & medicinal chemistry letters Feb 2012 - 1384-7 p. digital
Publication Type: Journal Article
1464-3405
10.1016/j.bmcl.2011.12.057 doi
Amides--chemical synthesis
Aminobenzoates--chemical synthesis
Animals
Cyclization
Humans
Inhibitory Concentration 50
Mice
Microsomes--enzymology
Models, Molecular
Molecular Structure
Protein Binding--drug effects
Rats
Receptors, CCR2--antagonists & inhibitors
Stereoisomerism
Structure-Activity Relationship
Substrate Specificity
Sulfur--chemistry
Synthesis of 3-phenylsulfonylmethyl cyclohexylaminobenzamide-derived antagonists of CC chemokine receptor 2 (CCR2). [electronic resource] - Bioorganic & medicinal chemistry letters Feb 2012 - 1384-7 p. digital
Publication Type: Journal Article
1464-3405
10.1016/j.bmcl.2011.12.057 doi
Amides--chemical synthesis
Aminobenzoates--chemical synthesis
Animals
Cyclization
Humans
Inhibitory Concentration 50
Mice
Microsomes--enzymology
Models, Molecular
Molecular Structure
Protein Binding--drug effects
Rats
Receptors, CCR2--antagonists & inhibitors
Stereoisomerism
Structure-Activity Relationship
Substrate Specificity
Sulfur--chemistry