Cdc6 protein activates p27KIP1-bound Cdk2 protein only after the bound p27 protein undergoes C-terminal phosphorylation.

Uranbileg, Baasanjav

Cdc6 protein activates p27KIP1-bound Cdk2 protein only after the bound p27 protein undergoes C-terminal phosphorylation. [electronic resource] - The Journal of biological chemistry Feb 2012 - 6275-83 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.M111.318295 doi


Amino Acid Substitution--physiology
Animals
Cell Cycle Proteins--chemistry
Cell Division--physiology
Cells, Cultured
Cyclin D3--genetics
Cyclin-Dependent Kinase 2--metabolism
Cyclin-Dependent Kinase Inhibitor p27--chemistry
Cytoskeleton--physiology
Enzyme Activation--physiology
Fibroblasts--cytology
Humans
Mice
Monomeric GTP-Binding Proteins--metabolism
Neuropeptides--metabolism
Nuclear Proteins--chemistry
Phosphorylation--physiology
Protein Binding--physiology
Protein Structure, Tertiary--physiology
RNA, Small Interfering--pharmacology
Ras Homolog Enriched in Brain Protein
Rats
Threonine--metabolism
rho-Associated Kinases--metabolism