Design and synthesis of potent carboxylic acid DGAT1 inhibitors with high cell permeability.

Bali, Ustav

Design and synthesis of potent carboxylic acid DGAT1 inhibitors with high cell permeability. [electronic resource] - Bioorganic & medicinal chemistry letters Jan 2012 - 824-8 p. digital

Publication Type: Journal Article

1464-3405

10.1016/j.bmcl.2011.12.050 doi


Caco-2 Cells
Diacylglycerol O-Acyltransferase--antagonists & inhibitors
Dose-Response Relationship, Drug
Drug Design
Enzyme Inhibitors--chemical synthesis
Humans
Molecular Structure
Permeability--drug effects
Structure-Activity Relationship