Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations.
Xu, Yechun
Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations. [electronic resource] - Acta crystallographica. Section D, Biological crystallography Jan 2012 - 13-25 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1399-0047
10.1107/S0907444911047251 doi
Amyloid Precursor Protein Secretases--chemistry
Aspartic Acid Endopeptidases--chemistry
Catalytic Domain
Crystallography, X-Ray
Humans
Hydrogen Bonding
Ligands
Models, Molecular
Molecular Dynamics Simulation
Protein Structure, Quaternary
Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations. [electronic resource] - Acta crystallographica. Section D, Biological crystallography Jan 2012 - 13-25 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1399-0047
10.1107/S0907444911047251 doi
Amyloid Precursor Protein Secretases--chemistry
Aspartic Acid Endopeptidases--chemistry
Catalytic Domain
Crystallography, X-Ray
Humans
Hydrogen Bonding
Ligands
Models, Molecular
Molecular Dynamics Simulation
Protein Structure, Quaternary