BRCA1 is an essential mediator of vinorelbine-induced apoptosis in mesothelioma.

Busacca, Sara

BRCA1 is an essential mediator of vinorelbine-induced apoptosis in mesothelioma. [electronic resource] - The Journal of pathology Jun 2012 - 200-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1096-9896

10.1002/path.3979 doi


Antineoplastic Agents, Phytogenic--pharmacology
Apoptosis--drug effects
BRCA1 Protein--genetics
Biomarkers, Tumor--genetics
Cell Line, Tumor
Cell Survival--drug effects
Dose-Response Relationship, Drug
Drug Resistance, Neoplasm--genetics
Humans
Immunohistochemistry
Inhibitory Concentration 50
Mesothelioma--genetics
Pleural Neoplasms--genetics
RNA Interference
Transfection
Vinblastine--analogs & derivatives
Vinorelbine