Foretinib demonstrates anti-tumor activity and improves overall survival in preclinical models of hepatocellular carcinoma.

Huynh, Hung

Foretinib demonstrates anti-tumor activity and improves overall survival in preclinical models of hepatocellular carcinoma. [electronic resource] - Angiogenesis Mar 2012 - 59-70 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1573-7209

10.1007/s10456-011-9243-z doi


Anilides--pharmacology
Animals
Antineoplastic Agents--therapeutic use
Apoptosis--drug effects
Carcinoma, Hepatocellular--blood supply
Cell Cycle--drug effects
Cell Line, Tumor
Cell Movement--drug effects
Cell Proliferation--drug effects
Disease Models, Animal
Dose-Response Relationship, Drug
Humans
Liver Neoplasms--blood supply
Male
Mice
Mice, SCID
Neovascularization, Pathologic--drug therapy
Quinolines--pharmacology
Survival Analysis
Time Factors
Xenograft Model Antitumor Assays