In vivo delivery of nucleic acids via glycopolymer vehicles affords therapeutic infarct size reduction in vivo.

Tranter, Michael

In vivo delivery of nucleic acids via glycopolymer vehicles affords therapeutic infarct size reduction in vivo. [electronic resource] - Molecular therapy : the journal of the American Society of Gene Therapy Mar 2012 - 601-8 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1525-0024

10.1038/mt.2011.267 doi


Animals
Cell Line
Cells, Cultured
Drug Delivery Systems
Gene Expression
Gene Silencing
Gene Transfer Techniques
Heart Ventricles--metabolism
Mice
Mice, Inbred C57BL
Myoblasts, Cardiac--metabolism
Myocardial Reperfusion Injury--genetics
Myocytes, Cardiac--metabolism
NF-kappa B--antagonists & inhibitors
Nanoconjugates--therapeutic use
Oligodeoxyribonucleotides--chemistry
Polymers--chemistry
Rats
Rats, Wistar
Transduction, Genetic