Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation.

Gagliani, Nicola

Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation. [electronic resource] - PloS one 2011 - e28434 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0028434 doi


Animals
Antibodies, Monoclonal--immunology
CD4 Antigens--metabolism
Drug Therapy, Combination
Epitopes--immunology
Female
Forkhead Transcription Factors--metabolism
Granulocyte Colony-Stimulating Factor--pharmacology
Humans
Immune Tolerance--drug effects
Interleukin-10--pharmacology
Interleukin-2 Receptor alpha Subunit--metabolism
Islets of Langerhans Transplantation
Leukocyte Common Antigens--immunology
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Models, Animal
Sirolimus--pharmacology
Spleen--drug effects
T-Lymphocytes, Regulatory--drug effects
Time Factors
Transplantation, Homologous