Aerosolized clindamycin is superior to aerosolized dexamethasone or clindamycin-dexamethasone combination in the treatment of severe Porphyromonas gingivalis aspiration pneumonia in an experimental murine model.

Nemec, Ana

Aerosolized clindamycin is superior to aerosolized dexamethasone or clindamycin-dexamethasone combination in the treatment of severe Porphyromonas gingivalis aspiration pneumonia in an experimental murine model. [electronic resource] - Experimental lung research Feb 2012 - 9-18 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1521-0499

10.3109/01902148.2011.632063 doi


Administration, Inhalation
Animals
Anti-Bacterial Agents--administration & dosage
Bacteroidaceae Infections--drug therapy
Bronchopneumonia--drug therapy
Chemotherapy, Adjuvant--methods
Clindamycin--administration & dosage
Dexamethasone--administration & dosage
Disease Models, Animal
Interleukin-1beta--blood
Interleukin-6--blood
Lung--drug effects
Male
Mice
Mice, Inbred BALB C
Nasal Sprays
Pneumonia, Aspiration--drug therapy
Porphyromonas gingivalis--isolation & purification
Receptors, Tumor Necrosis Factor, Type I--blood
Receptors, Tumor Necrosis Factor, Type II--blood
Tumor Necrosis Factor-alpha--blood