Comparing antihypertensive effect and plasma ciclosporin concentration between amlodipine and valsartan regimens in hypertensive renal transplant patients receiving ciclosporin therapy.

Cai, Jingjing

Comparing antihypertensive effect and plasma ciclosporin concentration between amlodipine and valsartan regimens in hypertensive renal transplant patients receiving ciclosporin therapy. [electronic resource] - American journal of cardiovascular drugs : drugs, devices, and other interventions Dec 2011 - 401-9 p. digital

Publication Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

1179-187X

10.2165/11593800-000000000-00000 doi


ATP Binding Cassette Transporter, Subfamily B
ATP Binding Cassette Transporter, Subfamily B, Member 1--genetics
Adult
Amlodipine--pharmacology
Antihypertensive Agents--pharmacology
Blood Pressure--drug effects
Cyclosporine--pharmacokinetics
Cytochrome P-450 CYP3A--genetics
Double-Blind Method
Drug Interactions
Female
Genotype
Humans
Hypertension--drug therapy
Immunosuppressive Agents--pharmacokinetics
Kidney Transplantation--methods
Male
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Prospective Studies
Tetrazoles--pharmacology
Valine--analogs & derivatives
Valsartan