Essential role of the adaptor protein Nck1 in Jurkat T cell activation and function.

Yiemwattana, I

Essential role of the adaptor protein Nck1 in Jurkat T cell activation and function. [electronic resource] - Clinical and experimental immunology Jan 2012 - 99-107 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1365-2249

10.1111/j.1365-2249.2011.04494.x doi


Adaptive Immunity--immunology
Adaptor Proteins, Signal Transducing--antagonists & inhibitors
Antibodies, Monoclonal--immunology
Antigens, CD--biosynthesis
Antigens, Differentiation, T-Lymphocyte--biosynthesis
Apoptosis--drug effects
CD28 Antigens--immunology
CD4-Positive T-Lymphocytes--immunology
Electroporation
Humans
Interleukin-1--biosynthesis
Jurkat Cells--drug effects
Lectins, C-Type--biosynthesis
Lymphocyte Activation--drug effects
Mitogen-Activated Protein Kinase 1--metabolism
Mitogen-Activated Protein Kinase 3--metabolism
Oncogene Proteins--antagonists & inhibitors
Phosphorylation
Phytohemagglutinins--pharmacology
Protein Processing, Post-Translational
RNA Interference
RNA, Small Interfering--pharmacology
Receptor-CD3 Complex, Antigen, T-Cell--immunology
Tetradecanoylphorbol Acetate--pharmacology