Endothelin-1 stimulates DNA synthesis and anchorage-independent growth of Rat-1 fibroblasts through a protein kinase C-dependent mechanism.

Muldoon, L L

Endothelin-1 stimulates DNA synthesis and anchorage-independent growth of Rat-1 fibroblasts through a protein kinase C-dependent mechanism. [electronic resource] - Cell regulation Mar 1990 - 379-90 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1044-2030

10.1091/mbc.1.4.379 doi


Animals
Cell Division--drug effects
Cell Line
DNA Replication--drug effects
DNA-Binding Proteins--biosynthesis
Diglycerides--metabolism
Endothelins--pharmacology
Epidermal Growth Factor--pharmacology
Fibroblasts--drug effects
Gene Expression Regulation--drug effects
Histones--metabolism
Phosphorylation
Protein Kinase C--antagonists & inhibitors
Protein Processing, Post-Translational--drug effects
Proto-Oncogene Proteins--biosynthesis
Proto-Oncogene Proteins c-fos
Proto-Oncogene Proteins c-jun
Rats
Second Messenger Systems--drug effects
Stimulation, Chemical
Tetradecanoylphorbol Acetate--pharmacology
Transcription Factors--biosynthesis
Transcription, Genetic--drug effects