A targeted siRNA screen identifies regulators of Cdc42 activity at the natural killer cell immunological synapse.

Carlin, Leo M

A targeted siRNA screen identifies regulators of Cdc42 activity at the natural killer cell immunological synapse. [electronic resource] - Science signaling Nov 2011 - ra81 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1937-9145

10.1126/scisignal.2001729 doi


Biological Clocks--genetics
Cell Line, Transformed
Cell- and Tissue-Based Therapy--methods
Class Ia Phosphatidylinositol 3-Kinase--genetics
Cytoskeleton--genetics
Enzyme Activation--genetics
Guanine Nucleotide Exchange Factors--genetics
Humans
Immunity, Cellular--genetics
Immunity, Innate--genetics
Immunological Synapses--enzymology
Killer Cells, Natural--enzymology
Neoplasms--enzymology
Proto-Oncogene Proteins c-akt
RNA, Small Interfering
Rho Guanine Nucleotide Exchange Factors
cdc42 GTP-Binding Protein--genetics