Oxidative DNA damage following microsome/Cu(II)-mediated activation of the estrogens, 17β-estradiol, equilenin, and equilin: role of reactive oxygen species.
Spencer, Wendy A
Oxidative DNA damage following microsome/Cu(II)-mediated activation of the estrogens, 17β-estradiol, equilenin, and equilin: role of reactive oxygen species. [electronic resource] - Chemical research in toxicology Feb 2012 - 305-14 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1520-5010
10.1021/tx200356v doi
8-Hydroxy-2'-Deoxyguanosine
Animals
Copper--pharmacology
DNA Adducts--metabolism
DNA Damage
Deoxyguanosine--analogs & derivatives
Estradiol Congeners--toxicity
Estrogens--toxicity
Female
Humans
Male
Mice
Microsomes, Liver--drug effects
Oxidation-Reduction
Rats
Rats, Sprague-Dawley
Reactive Oxygen Species--metabolism
Oxidative DNA damage following microsome/Cu(II)-mediated activation of the estrogens, 17β-estradiol, equilenin, and equilin: role of reactive oxygen species. [electronic resource] - Chemical research in toxicology Feb 2012 - 305-14 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1520-5010
10.1021/tx200356v doi
8-Hydroxy-2'-Deoxyguanosine
Animals
Copper--pharmacology
DNA Adducts--metabolism
DNA Damage
Deoxyguanosine--analogs & derivatives
Estradiol Congeners--toxicity
Estrogens--toxicity
Female
Humans
Male
Mice
Microsomes, Liver--drug effects
Oxidation-Reduction
Rats
Rats, Sprague-Dawley
Reactive Oxygen Species--metabolism