Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome.

Paşca, Sergiu P

Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome. [electronic resource] - Nature medicine Nov 2011 - 1657-62 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1546-170X

10.1038/nm.2576 doi


Autistic Disorder--genetics
Calcium Channels, L-Type--genetics
Calcium Signaling--drug effects
Cell Differentiation
Cell Line
Dopamine--metabolism
Gene Expression Regulation
Humans
Induced Pluripotent Stem Cells--cytology
Long QT Syndrome--enzymology
Microarray Analysis
Neurons--cytology
Norepinephrine--metabolism
Phenotype
Purines--pharmacology
Roscovitine
Syndactyly--enzymology
Tyrosine 3-Monooxygenase--genetics