Improved oral bioavailability of lopinavir in melt-extruded tablet formulation reduces impact of third trimester on lopinavir plasma concentrations.

Else, L J

Improved oral bioavailability of lopinavir in melt-extruded tablet formulation reduces impact of third trimester on lopinavir plasma concentrations. [electronic resource] - Antimicrobial agents and chemotherapy Feb 2012 - 816-24 p. digital

Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't

1098-6596

10.1128/AAC.05186-11 doi


Adolescent
Anti-HIV Agents--administration & dosage
Biological Availability
Capsules
Cohort Studies
Dose-Response Relationship, Drug
Female
Gelatin
HIV Infections--drug therapy
HIV Protease Inhibitors--administration & dosage
Humans
Lopinavir--administration & dosage
Pregnancy
Pregnancy Complications, Infectious--drug therapy
Pregnancy Trimester, Second
Pregnancy Trimester, Third
Tablets
Viral Load
Young Adult