Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils.

Bieschke, Jan

Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils. [electronic resource] - Nature chemical biology Nov 2011 - 93-101 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1552-4469

10.1038/nchembio.719 doi


Amino Acid Sequence
Amyloid--chemistry
Cell Line, Tumor
Hippocampus--chemistry
Humans
Hydrophobic and Hydrophilic Interactions
Microscopy, Electron, Transmission
Models, Molecular
Oxazines--chemistry
Peptide Fragments--chemistry
Protein Structure, Secondary
Synaptic Transmission