Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase.

Powell, Rebecca D

Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase. [electronic resource] - The Journal of biological chemistry Dec 2011 - 43596-43600 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.C111.317628 doi


Animals
Autoimmune Diseases--genetics
Autoimmune Diseases of the Nervous System--genetics
Catalysis
Cattle
Deoxyguanine Nucleotides--chemistry
Dose-Response Relationship, Drug
HIV-1--genetics
Humans
Mice
Monomeric GTP-Binding Proteins--chemistry
Myeloid Cells--cytology
Nervous System Malformations--genetics
Nucleosides--chemistry
Phosphoric Monoester Hydrolases--chemistry
SAM Domain and HD Domain-Containing Protein 1
Viral Regulatory and Accessory Proteins--metabolism
Virus Replication