Loading-related regulation of transcription factor EGR2/Krox-20 in bone cells is ERK1/2 protein-mediated and prostaglandin, Wnt signaling pathway-, and insulin-like growth factor-I axis-dependent.

Zaman, Gul

Loading-related regulation of transcription factor EGR2/Krox-20 in bone cells is ERK1/2 protein-mediated and prostaglandin, Wnt signaling pathway-, and insulin-like growth factor-I axis-dependent. [electronic resource] - The Journal of biological chemistry Feb 2012 - 3946-62 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.M111.252742 doi


Animals
Bone and Bones--cytology
Carcinogens--pharmacology
Cell Line
Cyclic AMP--genetics
Cyclic AMP-Dependent Protein Kinases--genetics
Cyclooxygenase 2--genetics
Dinoprostone--genetics
Early Growth Response Protein 2--genetics
Female
Insulin-Like Growth Factor I--genetics
Integrin beta1--genetics
Integrin beta3--genetics
MAP Kinase Kinase 1--genetics
Mice
Mitogen-Activated Protein Kinase 3--genetics
Nitric Oxide--genetics
RNA, Messenger--biosynthesis
Receptors, Prostaglandin E, EP1 Subtype--genetics
Tetradecanoylphorbol Acetate--pharmacology
Up-Regulation--drug effects
Wnt Signaling Pathway--drug effects
Wnt3A Protein--genetics