Evaluation of prothrombin complex concentrate and recombinant activated factor VII to reverse rivaroxaban in a rabbit model.

Godier, Anne

Evaluation of prothrombin complex concentrate and recombinant activated factor VII to reverse rivaroxaban in a rabbit model. [electronic resource] - Anesthesiology Jan 2012 - 94-102 p. digital

Publication Type: Journal Article

1528-1175

10.1097/ALN.0b013e318238c036 doi


Anesthesia
Animals
Anticoagulants--antagonists & inhibitors
Bleeding Time
Blood Coagulation Tests
Blood Pressure--drug effects
Body Temperature--drug effects
Dose-Response Relationship, Drug
Factor VIIa--administration & dosage
Hemorrhage--blood
Liver--blood supply
Male
Monitoring, Physiologic
Morpholines--antagonists & inhibitors
Prothrombin--administration & dosage
Rabbits
Recombinant Proteins--administration & dosage
Respiration, Artificial
Rivaroxaban
Spleen--blood supply
Thiophenes--antagonists & inhibitors
Thrombelastography
Thrombin--biosynthesis
Thrombosis--blood