Microvascular disease precedes the decline in renal function in the streptozotocin-induced diabetic rat.

Maric-Bilkan, Christine

Microvascular disease precedes the decline in renal function in the streptozotocin-induced diabetic rat. [electronic resource] - American journal of physiology. Renal physiology Feb 2012 - F308-15 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1522-1466

10.1152/ajprenal.00421.2011 doi


Angiography--methods
Animals
Diabetes Mellitus, Experimental--diagnostic imaging
Diabetic Angiopathies--diagnostic imaging
Diabetic Nephropathies--diagnostic imaging
Disease Progression
Glomerular Filtration Rate--physiology
Kidney--blood supply
Male
Matrix Metalloproteinase 2--metabolism
Microcirculation--physiology
Rats
Rats, Sprague-Dawley
Renal Circulation--physiology
Tissue Inhibitor of Metalloproteinase-1--metabolism
Vascular Endothelial Growth Factor A--metabolism
Vascular Endothelial Growth Factor Receptor-1--metabolism
Vascular Endothelial Growth Factor Receptor-2--metabolism
X-Ray Microtomography