An activin receptor-like kinase 5 inhibitor reduces collagen deposition in a rat dermal incision wound healing model.

Bian, Feng

An activin receptor-like kinase 5 inhibitor reduces collagen deposition in a rat dermal incision wound healing model. [electronic resource] - Plastic and reconstructive surgery Nov 2011 - 451e-459e p. digital

Publication Type: Comparative Study; Journal Article

1529-4242

10.1097/PRS.0b013e31822b65c7 doi


Animals
Cell Proliferation--drug effects
Cicatrix--prevention & control
Collagen--drug effects
Dermatologic Surgical Procedures
Disease Models, Animal
Enzyme-Linked Immunosorbent Assay
Immunohistochemistry
Male
Protein Serine-Threonine Kinases--antagonists & inhibitors
Random Allocation
Rats
Rats, Sprague-Dawley
Real-Time Polymerase Chain Reaction
Receptor, Transforming Growth Factor-beta Type I
Receptors, Transforming Growth Factor beta--antagonists & inhibitors
Reference Values
Skin--drug effects
Transforming Growth Factor beta--antagonists & inhibitors
Wound Healing--drug effects
Wounds and Injuries--drug therapy