SYK inhibition and response prediction in diffuse large B-cell lymphoma.

Cheng, Shuhua

SYK inhibition and response prediction in diffuse large B-cell lymphoma. [electronic resource] - Blood Dec 2011 - 6342-52 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1528-0020

10.1182/blood-2011-02-333773 doi


Antineoplastic Agents--pharmacology
Biomarkers--metabolism
Cell Line, Tumor
Drug Resistance, Neoplasm
G1 Phase--drug effects
Gene Expression Regulation, Neoplastic
Humans
Intracellular Signaling Peptides and Proteins--antagonists & inhibitors
Lymph Nodes--drug effects
Lymphoma, Large B-Cell, Diffuse--drug therapy
Molecular Targeted Therapy
Neoplasm Proteins--antagonists & inhibitors
Phospholipase C gamma--antagonists & inhibitors
Phosphorylation--drug effects
Protein Kinase Inhibitors--pharmacology
Protein Processing, Post-Translational--drug effects
Protein-Tyrosine Kinases--antagonists & inhibitors
Proto-Oncogene Proteins c-akt--antagonists & inhibitors
RNA Interference
RNA, Messenger--metabolism
RNA, Small Interfering
Signal Transduction--drug effects
Syk Kinase
Tumor Cells, Cultured