The mammalian disaggregase machinery: Hsp110 synergizes with Hsp70 and Hsp40 to catalyze protein disaggregation and reactivation in a cell-free system.

Shorter, James

The mammalian disaggregase machinery: Hsp110 synergizes with Hsp70 and Hsp40 to catalyze protein disaggregation and reactivation in a cell-free system. [electronic resource] - PloS one 2011 - e26319 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0026319 doi


Adenosine Triphosphatases--metabolism
Adenosine Triphosphate--metabolism
Amyloid--metabolism
Animals
Biocatalysis
Cell-Free System
Conserved Sequence
Cytosol--enzymology
HSP110 Heat-Shock Proteins--chemistry
HSP40 Heat-Shock Proteins--chemistry
HSP70 Heat-Shock Proteins--chemistry
HeLa Cells
Humans
Hydrolysis
Mammals--metabolism
Protein Binding
Protein Structure, Quaternary
Rats
Saccharomyces cerevisiae--metabolism
Saccharomyces cerevisiae Proteins--metabolism
Substrate Specificity